Lab Associate

Opportunity

This role provides an opportunity to learn and grow as an expert in the field of antibody(mAbs) and protein biosimilars therapeutics characterization and analytical R&D for proteins.

Key Responsibilities

• Carryout in U(H)PLC and Mass Spectrometry based method development, qualification and characterization activities towards bio-similarity and comparability studies of monoclonal antibodies(mAbs) and therapeutic proteins.
• Perform Protein/Glycoprotein, and Glycan sample preparation, handling and storage for LC-MS based experiments.
• Perform peptide mapping digestions using various enzymes for LC-MS based experiments.
• Perform setup and raw data acquisition on U(H)PLC and Mass Spectrometry based experiments.
• Analyze, compile, and interpret data of various protein samples (R&D process samples, Final stage etc.) in an efficient and timely manner.
• Carry out LC-MS and characterization and allied method development/improvement trials whenever required.
• Maintain records and compliant documentation of all the analysis/experiments performed.

Accountabilities and Responsibilities

• Responsible for U(H)PLC-Mass Spectrometry based analysis of R&D project/process samples.
• Provide characterization/analytical support to process/internal teams as and when required.
• Ensure data integrity and good documentation practices.

Competencies

• Protein sample preparation techniques( Centrifugation/Concentration/Extraction etc.)
• Hands on common laboratory instruments UV-Vis Spectrometer,pH meter, weighing balances.
• Sound knowledge on ICH and other analytical guidelines.
• Key Operations and troubleshooting of HPLC/U(H)PLC and Mass Spectrometry based experiments.
• Good Hands on with Protein related Bioinformatics tools.
• Data evaluation with statistics and analytical thinking.
• Good documentation practices using MS office.
• Good oral and written communication.